產品貨號 :  mlR3662

英文名稱 :  WNT10B

中文名稱 :  信號通路WNT10B抗體

別    名 :  WN10B_HUMAN; SHFM6; wingless type MMTV integration site family, member 10B; wnt12; WNT10B; WNT10-B.  

研究領域 :  腫瘤  免疫學  信號轉導  轉錄調節因子  

抗體來源 :  Rabbit

克隆類型 :  Polyclonal

交叉反應 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,

產品應用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  40kDa

細胞定位 :  細胞漿 分泌型蛋白

性    狀 :  Lyophilized or Liquid

濃    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human WNT12:201-300/389

亞    型 :  IgG

純化方法 :  affinity purified by Protein A

儲 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

產品介紹 :   Wnts comprise a family of secreted signaling proteins that regulate diverse developmental processes. Activation of Wnt signaling by Wnt10b inhibits differentiation of preadipocytes and blocks adipose tissue development. In bone development, Wnt10b shifts cell fate toward the osteoblast lineage.

Subcellular Location:

Secreted, extracellular space, extracellular matrix.

Tissue Specificity:

Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain.

Similarity:

Belongs to the Wnt family.

SWISS:

O00744

Gene ID:

7480

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.