產(chǎn)品貨號 :  mlR6478

英文名稱 :  Carboxypeptidase H

中文名稱 :  胰羧肽酶E抗體

別    名 :  Carboxypeptidase E; Carboxypeptidase-E; Carboxypeptidase H; Carboxypeptidase H precursor; CarboxypeptidaseE; CarboxypeptidaseH; CBPE_HUMAN; CPE; Cph 1; CPH; Cph1; Enkephalin convertase; Entephalin convertase; Prohormone processing carboxypeptidase; Prohormone-processing carboxypeptidase.  

研究領(lǐng)域 :  腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  生長因子和激素  糖尿病  內(nèi)分泌病  

抗體來源 :  Rabbit

克隆類型 :  Polyclonal

交叉反應(yīng)  :  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,

產(chǎn)品應(yīng)用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 （石蠟切片需做抗原修復(fù)）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  48kDa

細(xì)胞定位 :  細(xì)胞核 細(xì)胞漿 細(xì)胞膜 分泌型蛋白

性    狀 :  Lyophilized or Liquid

濃    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Carboxypeptidase E:201-300/476

亞    型 :  IgG

純化方法 :  affinity purified by Protein A

儲 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

產(chǎn)品介紹background :  

Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.

Subcellular Location:

Isoform 1: Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions.

soform 2: Nucleus.

Tissue Specificity:

Isoform 2, but not isoform 1, is overexpressed in hepatocellular carcinoma (at protein level), as well as in other tumors, including pheochromocytomas and paragangliomas.

Similarity:

Belongs to the peptidase M14 family.

SWISS:

P16870

Gene ID:

1363

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.