產品貨號 :  mlR20723

英文名稱 :  SLC22A11

中文名稱 :  有機陰離子轉運體4抗體

別    名 :  hOAT4; MGC34282; OAT4; Organic anion transporter 4; Solute carrier family 22 (organic anion/urate transporter) member 11; Solute carrier family 22 member 11.   

研究領域 :  腫瘤  信號轉導  生長因子和激素  通道蛋白  

抗體來源 :  Rabbit

克隆類型 :  Polyclonal

交叉反應 :   Human,

產品應用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  60kDa

細胞定位 :  細胞膜

性    狀 :  Lyophilized or Liquid

濃    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human SLC22A11:21-120/550 <Extracellular>

亞    型 :  IgG

純化方法 :  affinity purified by Protein A

儲 存 液 :  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存條件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

產品介紹background:

The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Function:

Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.

Subcellular Location:

Cell membrane, Multi-pass membrane protein.

Tissue Specificity:

Detected in placenta and kidney.

Post-translational modifications:

N-glycosylated. Contains several complex-type N-glycans.

Similarity:

Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

SWISS:

Q9NSA0

Gene ID:

55867

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產品圖片