產品貨號 :  mlR8298

英文名稱 :  UQCRC1

中文名稱 :  輔酶細胞色素C還原酶核心蛋白1抗體

別   名 :  Ubiquinol-Cytochrome C Reductase Core Protein I; mitochondrial; Complex III subunit 1; Core protein I; Cytochrome b c1 complex subunit 1, mitochondrial; Cytochrome b-c1 complex subunit 1; D3S3191; OTTHUMP00000164820; QCR1; QCR1_HUMAN; Ubiquinol cytochrome c reductase core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1; UQCR1; UQCRC1.  

研究領域 :  細胞生物  信號轉導  線粒體  

抗體來源 :  Rabbit

克隆類型 :  Polyclonal

交叉反應  :  Human, Mouse, Rat, Cow, Monkey, y

產品應用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蠟切片需做抗原修復）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  49kDa

細胞定位 :  細胞漿 細胞膜 線粒體

性    狀 :  Lyophilized or Liquid

濃    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human UQCRC1:65-170/480

亞    型 :  IgG

純化方法 :  affinity purified by Protein A

儲 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

產品介紹 :   This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.

Function:

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.

Subunit:

The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).

Subcellular Location:

Mitochondrion inner membrane.

Post-translational modifications:

Acetylation of Lys-138 is observed in liver mitochondria from fasted mice but not from fed mice.

Similarity:

Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.

SWISS:

P31930

Gene ID:

54878

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產品圖片