產品貨號 : mlR16899
英文名稱 : KCNK16
中文名稱 : 鉀離子通道蛋白16抗體
別 名 : 2P domain potassium channel Talk 1; pancreatic potassium channel Talk 1; potassium channel subfamily K member 16; TALK 1; KCNKG_HUMAN; TALK1; TWIK related alkaline pH activated K(+) channel 1.
研究領域 : 腫瘤 細胞生物 免疫學 神經生物學 通道蛋白
抗體來源 : Rabbit
克隆類型 : Polyclonal
交叉反應 : Human,
產品應用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 34kDa
細胞定位 : 細胞膜
性 狀 : Lyophilized or Liquid
濃 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human KCNK16:231-309/309
亞 型 : IgG
純化方法 : affinity purified by Protein A
儲 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
產品介紹background:
The protein encoded by the KCNK16 gene belongs to a family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH and is expressed predominantly in the pancreas. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Function:
Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.
Subunit:
Homodimer (Potential).
Subcellular Location:
Membrane; Multi-pass membrane protein
Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
SWISS:
Q96T55
Gene ID:
83795
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.