產品貨號 :  mlR6825

英文名稱 :  MAGEB6

中文名稱 :  黑色素瘤相關抗原B6抗體

別  名:  Cancer/testis antigen 3.4; CT3.4; MAGEB6 antigen; Melanoma associated antigen B6; MAGB6_HUMAN.  

研究領域 :  腫瘤  細胞類型標志物  腫瘤細胞生物標志物  

抗體來源 :  Rabbit

克隆類型 :  Polyclonal

交叉反應 :   Human,

產品應用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蠟切片需做抗原修復）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  44kDa

細胞定位 :  細胞核 細胞漿 細胞膜

性    狀 :  Lyophilized or Liquid

濃    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MAGEB6:151-250/407

亞    型 :  IgG

純化方法 :  affinity purified by Protein A

儲 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

產品介紹background:

The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different type of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta. Although a large number of MAGE genes have now been identified and extensively studied in tumors of various origin, their function in normal cells remains unknown. MAGE-B6 is expressed in testis and tumors of various histological origins but has not been shown to be expressed in other normal tissues.

Tissue Specificity:

Expressed in testis. Not expressed in other normal tissues, but is expressed in tumors of different histological origins.

Similarity:

Contains 1 MAGE domain.

SWISS:

Q8N7X4

Gene ID:

158809

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產品圖片