產(chǎn)品貨號(hào) :  mlR18616

英文名稱 :  MAGD4

中文名稱 :  黑色素瘤相關(guān)抗原D4抗體

別    名 :  Melanoma-associated antigen D4.  

研究領(lǐng)域 :  腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  泛素  

抗體來源 :  Rabbit

克隆類型 :  Polyclonal

交叉反應(yīng) :  Human, Cow,

產(chǎn)品應(yīng)用 :  IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  81kDa

細(xì)胞定位 :  細(xì)胞膜

性    狀 :  Lyophilized or Liquid

濃    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MAGD4:231-330/741

亞    型 :  IgG

純化方法 :  affinity purified by Protein A

儲(chǔ) 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

產(chǎn)品介紹 :  This gene is a member of the MAGED gene family. It is expressed only in brain and ovary, and some transcript variants of this gene are specifically expressed in glioma cells. This gene is clustered with other MAGED genes on chromosome Xp11. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]

Function:

May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.

Tissue Specificity:

Expressed only in brain and ovary among normal tissues. Isoform 1 and isoform 2 are specifically expressed in glioma cells among cancer cells. Detected in some renal cell carcinoma samples.

Similarity:

Contains 1 MAGE domain.

SWISS:

Q96JG8

Gene ID:

81557

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.